A study on the relative contents of CL-19-￣（131）I to NCL-6-￣（131）I in ￣（131）I-iodocholesterol

Huang Tiansen

您当前的位置：

首页 >

文章列表页 >

A study on the relative contents of CL-19-￣（131）I to NCL-6-￣（131）I in ￣（131）I-iodocholesterol

更新时间：2021-04-09

- A study on the relative contents of CL-19-￣（131）I to NCL-6-￣（131）I in ￣（131）I-iodocholesterol
- NUCLEAR TECHNIQUES Issue 5, (1995)
- 作者机构：
  
  上海市药品检验所
- 作者简介：
- 基金信息：
- DOI：
  CLC： O653
- Published：01 May 1995
- 稿件说明：
移动端阅览
[1]黄天森.碘［~（131）I］胆甾醇中19位和6位胆甾醇比值的探讨[J].核技术,1995(05):300-302.

Huang Tiansen. A study on the relative contents of CL-19-￣（131）I to NCL-6-￣（131）I in ￣（131）I-iodocholesterol[J]. Nuclear techniques, 1995, (5).
[1]黄天森.碘［~（131）I］胆甾醇中19位和6位胆甾醇比值的探讨[J].核技术,1995(05):300-302. DOI：

Huang Tiansen. A study on the relative contents of CL-19-￣（131）I to NCL-6-￣（131）I in ￣（131）I-iodocholesterol[J]. Nuclear techniques, 1995, (5). DOI：

摘要

采用薄板层析法测定碘［１３１Ｉ］胆甾醇中１９位和６位的比值，并对不同比值的七批供试品进行小白鼠肾上腺摄取率的对比试验，发现１９位和６位的比值愈高，肾上腺摄取率愈低。本品的热稳定性考察表明，比值愈高，对热愈不稳定。说明１９位热稳定性较６位差。证明作为肾上腺显像剂，６位是较理想的。

Abstract

The relative contents of CL-19-131I（131I-19-iodocholest-5-en-3β-ol）and NCL-6-131I（131I-6β-iodomethyl-19-norcholest-5（10）-en-3β-ol） in seven batches of 131I-iodocholesterol prepared by Shanghai First Chemical Reagent Factory were determined by means of thin layer chromatography. It was found that when the ratio of CL-19-131I to NCL-6-131I was calculated

there was a negative correlation between this ratio and the adrenal gland uptake of 131I.A negative correlation was also found between this ratio and the heat stability of 131I-iodocholesterol.Therefored NCL- 6- 131I appears to be the better imaging agent for adrenal medulla.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

AI问答

Address：2019 Jialuo Road, Jiading, Shanghai, China Postal code：201800
Tel：021-39194977 Email：LHB@sinap.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 沪ICP备05005479号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
Total Visits：880780 Visits Today：307

⁰