Kinetic study on ligand exchange reaction between EC and ￣（99m）Tc-GH

您当前的位置：

首页 >

文章列表页 >

Kinetic study on ligand exchange reaction between EC and ￣（99m）Tc-GH

更新时间：2021-04-09

- Kinetic study on ligand exchange reaction between EC and ￣（99m）Tc-GH
- NUCLEAR TECHNIQUES Issue 5, (1995)
- 作者机构：
  
  江苏省原子医学研究所核医学国家重点实验室
- 作者简介：
- 基金信息：
- DOI：
  CLC： TQ203.6
- Published：01 May 1995
- 稿件说明：
移动端阅览
[1]吴春英,罗世能,方平,黄荷芸,谢敏浩,孟虹.EC与~（99m）Tc－GH之间的配体交换反应动力学研究[J].核技术,1995(05):293-296.

Kinetic study on ligand exchange reaction between EC and ￣（99m）Tc-GH[J]. Nuclear techniques, 1995, (5).
[1]吴春英,罗世能,方平,黄荷芸,谢敏浩,孟虹.EC与~（99m）Tc－GH之间的配体交换反应动力学研究[J].核技术,1995(05):293-296. DOI：

Kinetic study on ligand exchange reaction between EC and ￣（99m）Tc-GH[J]. Nuclear techniques, 1995, (5). DOI：

摘要

实验表明，ＥＣ浓度与配体交换反应速度常数无关，体系的ｐＨ值对速度常数和９９ｍＴｃ－ＥＣ的标记率影响较大。测定并计算了不同ｐＨ值的交换反应速度常数。结果表明，为保证用配体交换法制备９９ｍｃ－ＥＣ时９９ｍｃ－ＥＣ的标记率大于９０％，体系的ｐＨ值必须≥８。

Abstract

The ligand exchange reaction between EC and 99mTc-GH and its influence factors such as concentrations of EC and pH were described in this paper.The concentration of EC has no influence on the exchange reaction rate constant

while pH is the most important influence factor.The rate constants of ligand exchange reaction at different pH values were determined.The results showed that in order to make the labelling yield of 99mTc-EC higher than 90%

pH of the reaction must be higher than 8.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Preparation and biodistribution of 99m TcN（DDC）2

A new method of indirect labelling monoclonal antibodies with 99m Tc

Clinical evaluation of ￣（99m）Tc uptake rate in functional image of thyroid

The preparation and biodistribution of ^99mTc-cyclohexanedione dioxime and its methaneboronic acid adduct

Studies on the kinetics of preparation reaction of ^99mTc-MIBI

Related Author

纪书仁

陈正平

吴春英

周翔

Fang Ping Zhou Xiang Wu Chunying Chen Zhengping Ji Shuren

张永学

安锐

Zhang Kaijun An Rui Zhang Yongxue Ye Weixin Gao Zairong

Related Institution

State Key Laboratory of Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wui 2140623)

Union Hospital, Tongji Medical University, Wuhan 430002)

同济医科大学实验中心

同济医科大学附属协和医院同济医科大学实验中心

Cancer Hospital, Shanghai Medical University

AI问答

Address：2019 Jialuo Road, Jiading, Shanghai, China Postal code：201800
Tel：021-39194977 Email：LHB@sinap.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 沪ICP备05005479号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
Total Visits：880780 Visits Today：307

⁰