Synthesis of precursor and radiolabelling of neuroreceptor imaging agent I-IBZM

您当前的位置：

首页 >

文章列表页 >

Synthesis of precursor and radiolabelling of neuroreceptor imaging agent I-IBZM

更新时间：2021-04-09

- Synthesis of precursor and radiolabelling of neuroreceptor imaging agent I-IBZM
- NUCLEAR TECHNIQUES Issue 11, (1995)
- 作者机构：
  
  上海医科大学药学院
- 作者简介：
- 基金信息：
- DOI：
  CLC： TQ572
- Published：01 November 1995
- 稿件说明：
移动端阅览
[1]沈鸣华,龚佳玲,李燕茹.神经受体显像剂放射性碘IBZM前体合成及碘标记[J].核技术,1995(11):648-650.

Synthesis of precursor and radiolabelling of neuroreceptor imaging agent I-IBZM[J]. Nuclear techniques, 1995, (11).
[1]沈鸣华,龚佳玲,李燕茹.神经受体显像剂放射性碘IBZM前体合成及碘标记[J].核技术,1995(11):648-650. DOI：

Synthesis of precursor and radiolabelling of neuroreceptor imaging agent I-IBZM[J]. Nuclear techniques, 1995, (11). DOI：

摘要

合成了苯酰胺类多巴胺Ｄ２受体显像剂Ｉ－ＩＢＺＭ的前体ＢＺＭ及非放射性ＩＢＺＭ，用氯胺－Ｔ法标记及用ＴＬＣ同时将游离碘、反应前体ＢＺＭ与产品Ｉ－ＩＢＺＭ分离，产品放化纯度＞９０％．（Ｓ）－（－）－１２５Ｉ－ＩＢＺＭ能与鼠脑纹状体膜受体制剂特异结合。

Abstract

This report describes the routine method for preparing BZM and IBZM.I-IBZM was prepared by the chloramine-T method and was purified by TLC.The radiochemical purity was better than 90%.（S）-（-）-125I-IBZM can specific bound with rat striatal homogenate in vitro.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Synthesis of precursor and radiolabelling of neuroreceptor imaging agent ￣（77）Br-p-bromospiroperidol

Related Author

黄永学

李永键

Related Institution

Shanghai Institute of Nuclear Research, Academia Sinica

都市卫生防疫站

AI问答

Address：2019 Jialuo Road, Jiading, Shanghai, China Postal code：201800
Tel：021-39194977 Email：LHB@sinap.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 沪ICP备05005479号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
Total Visits：880780 Visits Today：307

⁰