Use of micronucleus test in evaluating radioprotective action of mixed tremella preparation

Lu Jiaben Huang Yinmei Zhu Bingchai

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Use of micronucleus test in evaluating radioprotective action of mixed tremella preparation

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- Use of micronucleus test in evaluating radioprotective action of mixed tremella preparation
- NUCLEAR TECHNIQUES Issue 5, (1993)
- 作者机构：
  
  1. 海军医学研究所
  2. 海军医学研究所,上海,200433
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：01 May 1993
- 稿件说明：
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[1]吕家本,黄银妹,朱炳钗.用微核试验来评价复方银耳制剂的抗辐射作用[J].核技术,1993(05):317-320.

Lu Jiaben Huang Yinmei Zhu Bingchai. Use of micronucleus test in evaluating radioprotective action of mixed tremella preparation[J]. Nuclear techniques, 1993, (5): 317-320.
[1]吕家本,黄银妹,朱炳钗.用微核试验来评价复方银耳制剂的抗辐射作用[J].核技术,1993(05):317-320. DOI：

Lu Jiaben Huang Yinmei Zhu Bingchai. Use of micronucleus test in evaluating radioprotective action of mixed tremella preparation[J]. Nuclear techniques, 1993, (5): 317-320. DOI：

摘要

采用微核试验来评价一种抗辐射新药复方银耳制剂（下称银参饮）对受1Gyγ射线急性照射犬的辐射防护作用。实验分成银耳

胱胺

银参饮高、低剂量及照射对照五个组。结果显示

预防服用银参饮具有良好的抗辐射作用

其抗放效价类似于胱胺而明显高于银耳组。各组的剂量减低系数分别为:银参饮高剂量组2.01、银参饮低剂量组1.72、胱胺组1.55、银耳组1.11。

Abstract

The radioprotective action of mixed tremella preparation（Yinshen Yin） on whole body gamma irradiated dogs has been studied. 25 male dogs were divided into five groups: tremella

mercaminum

Yinshen Yin at high dose

Yinshen Yin at low dose and control. All the dogs were given above drugs in 10 successive days before acute exposure of 1 Gy radiation. The results showed that the prophylaxtic use of Yinshen Yin had good anti- irradiation effect

and the radioprotective effect was similar to the mercaminum

but significantly higher than tremella. Thereby it was considered as a good radioprotective agent. The dose reduction factor in different groups were: Yinshen Yin high dose 2.01

Yinshen Yin low dose group 1.72

mercaminum group 1.55 and tremella group 1.11.

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