Synthesis of the 1-aminocylopropane-1-carboxylic acid

Li Lu Lin Fenzhi

您当前的位置：

首页 >

文章列表页 >

Synthesis of the 1-aminocylopropane-1-carboxylic acid

更新时间：2021-04-09

- Synthesis of the 1-aminocylopropane-1-carboxylic acid
- NUCLEAR TECHNIQUES Issue 1, (1992)
- 作者机构：
  
  1. 中国科学院上海原子核研究所
  2. 中国科学院上海原子核研究所,上海,201800
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：01 January 1992
- 稿件说明：
移动端阅览
[1]李侣,林奋智.[~(14)C-羧基]-1-氨基环丙烷-1-羧酸的合成[J].核技术,1992(01):43-45.

Li Lu Lin Fenzhi. Synthesis of the 1-aminocylopropane-1-carboxylic acid[J]. Nuclear techniques, 1992, (1): 43-45.
[1]李侣,林奋智.[~(14)C-羧基]-1-氨基环丙烷-1-羧酸的合成[J].核技术,1992(01):43-45. DOI：

Li Lu Lin Fenzhi. Synthesis of the 1-aminocylopropane-1-carboxylic acid[J]. Nuclear techniques, 1992, (1): 43-45. DOI：

摘要

本文报道以Ba

为起始原料制备

KCN

合成

C-甘氨酸的对-溴苯甲亚胺衍生物

然后在DMF和无水K

体系中

加1、2-二溴乙烷进行环丙烷化

经盐酸水解

得到[

C-羧基]-1-氨基环丙烷-1-羧酸(

C-ACC)。放化产率:K

CN94.3％.

C-甘氨酸90％

C-ACC52％。化学纯度和放化纯度均达99％。

Abstract

This paper is about the preparation method of ACC. The finely divided barium carbonate-14C is used to react with sodium azide to obtain potassium cyanide-14C. From potassium cyanide-14C

the derivative of p-bromo-benzoic imine of glycine-14C is synthesized. The derivative is dissolved in DMF containing anhydrous K2CO3.The mixture is refluxed with 1.2-dibromo-ethane extracted and depurated under absolute ether. The residure is hydrolyzed by refluxing with 2mol/l HCl. Finally the 1-amino-cylopropane-l-carboxylic acid（ACC） is obtained. The yield of K14CN

14-Gly

14C-ACC are 94.3%

90%

52% respectively. The ACC is purified and both the chemical purity and radioactive purity of ACC are 99%.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

AI问答

Address：2019 Jialuo Road, Jiading, Shanghai, China Postal code：201800
Tel：021-39194977 Email：LHB@sinap.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 沪ICP备05005479号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
Total Visits：880718 Visits Today：245

⁰