Studies on acute toxicity and mutagenicity of <sup>6</sup>0Co irradiated pollens

Yang Yongnian Tang Lingfang

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Studies on acute toxicity and mutagenicity of ⁶0Co irradiated pollens

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- Studies on acute toxicity and mutagenicity of ⁶0Co irradiated pollens
- NUCLEAR TECHNIQUES Issue 10, (1992)
- 作者机构：
  
  1. 南京医学院
  2. 南京医学院,南京,210029
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：01 October 1992
- 稿件说明：
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[1]杨永年,唐玲芳.~(60)Co辐照花粉在小鼠体内的急性毒性和诱变性研究[J].核技术,1992(10):621-624.

Yang Yongnian Tang Lingfang. Studies on acute toxicity and mutagenicity of ⁶0Co irradiated pollens[J]. Nuclear techniques, 1992, (10): 621-624.
[1]杨永年,唐玲芳.~(60)Co辐照花粉在小鼠体内的急性毒性和诱变性研究[J].核技术,1992(10):621-624. DOI：

Yang Yongnian Tang Lingfang. Studies on acute toxicity and mutagenicity of ⁶0Co irradiated pollens[J]. Nuclear techniques, 1992, (10): 621-624. DOI：

摘要

急性毒性试验小鼠经口给

Co辐照花粉

雌雄两性小鼠的LD

均

21500mg/kg

表明辐照花粉属实际无毒级。用三种短期试验进行诱变性检测

Ames试验对TA

、TA

100

及TA

102

四种菌株皆不能引起诱变。骨髓细胞微核试验阴性。精原细胞染色体畸变分析未见畸变率增加。上述结果表明辐照花粉对人体服用是安全的。

Abstract

The acute toxicity test showed that the oral LD50values were >21500mg/kg for male and female mice

indicating that irradiated pollens belong to low toxicity grade or practically non-toxic . Mutagenicities were studied in three short-term tests. Ames test showed that ir-radia-ted pollens did not induce mutation towards strains TA98

TA97

TA100and TA102. Mi-cronucleus test in the bone marrow cells indicated that the percentage of polychromatic ery-throcytes with micronuclei in exposed groups had no significant difference in comparison with the controlled ones . Chromosomal test for reproduction cells showed that the increase of chromosomal aberration rate was not observed . All the above results suggest that irradiated pollens are safe for human consumption.

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Studies on acute toxicity and mutagenicity of 60Co irradiated pollens

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Abstract

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Studies on acute toxicity and mutagenicity of ⁶0Co irradiated pollens