Influence of irradiation sterilization on mechanical properties and biodegradability of chitosan conduits

CAO Wenling LI Jing JING Duohui GONG Yandao ZHAO Nanming ZHANG Xiufang

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Influence of irradiation sterilization on mechanical properties and biodegradability of chitosan conduits

更新时间：2021-03-12

- Influence of irradiation sterilization on mechanical properties and biodegradability of chitosan conduits
- NUCLEAR TECHNIQUES Issue 3, (2005)
- 作者机构：
  
  1. 清华大学生物科学与技术系生物膜与膜生物工程国家重点实验室
  2. 清华大学生物科学与技术系生物膜与膜生物工程国家重点实验室,北京,100084
- 作者简介：
- 基金信息：
  
  国家“863”计划项目 (2001AA620506);国家“973” 计划项目(G1999064702) 资助
- DOI：
  CLC： R318.08
- Published：01 March 2005
- 稿件说明：
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[1]曹文灵,李静,井多辉,公衍道,赵南明,张秀芳.辐射灭菌对壳聚糖管力学性能和生物降解性的影响研究[J].核技术,2005(03):187-191.

CAO Wenling LI Jing JING Duohui GONG Yandao ZHAO Nanming ZHANG Xiufang. Influence of irradiation sterilization on mechanical properties and biodegradability of chitosan conduits[J]. Nuclear techniques, 2005, (3): 187-191.
[1]曹文灵,李静,井多辉,公衍道,赵南明,张秀芳.辐射灭菌对壳聚糖管力学性能和生物降解性的影响研究[J].核技术,2005(03):187-191. DOI：

CAO Wenling LI Jing JING Duohui GONG Yandao ZHAO Nanming ZHANG Xiufang. Influence of irradiation sterilization on mechanical properties and biodegradability of chitosan conduits[J]. Nuclear techniques, 2005, (3): 187-191. DOI：

摘要

采用剂量为 25 kGy 的 γ 射线对壳聚糖管进行辐射灭菌

并测试了其体外降解性能、溶胀性能和力学性能。结果表明

γ 射线辐射灭菌明显降低了溶菌酶对壳聚糖管的降解速率和其在水溶液中的溶胀

并显著提高了其拉伸强度和弹性模量。同时

运用傅里叶红外光谱（FTIR）、X 射线衍射（XRD）和差热分析（DSC）表征了辐射灭菌前后壳聚糖材料的化学结构和结晶形态

探讨了辐射灭菌对壳聚糖管性能影响的机制。

Abstract

Chitosan conduits were sterilized with 60Co γ ray irradiation at a dose of 25 kGy and their swelling properties

mechanical properties and biodegradability in lysozyme solution were measured. After γ ray irradiation

the swelling index of chitosan conduit was considerably reduced and the tensile strength and elastic modulus were markedly increased. The results from SEM and measurement of mechanical properties showed that the degradation rate of the irradiated conduits in lysozyme solution was lower than that of the nonirradiated conduits. In addition

the chitosan conduits were characterized by Fourier transform infrared spectroscopy (FTIR)

X-ray diffraction (XRD) and differential scanning calorimeter (DSC)

and the influence mechanism of irradiation sterilization on the properties of chitosan conduits was explored.

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Related Institution

Physics Department, Guangxi University, Nanning 530004) 2

中国科学院国际材料物理中心

中国科学院金属研究所

中国科学院国际材料物理中心南宁530004中国科学院国际材料物理中心沈阳

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