Hormesis and adaptive response of survival in HeLa cells  induced by low dose X-ray irradiation

LI Wenjian  1  LIANG Ke  2  SHEN Yu  2  1

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Hormesis and adaptive response of survival in HeLa cells induced by low dose X-ray irradiation

更新时间：2021-03-12

- Hormesis and adaptive response of survival in HeLa cells induced by low dose X-ray irradiation
- NUCLEAR TECHNIQUES Issue 3, (2002)
- 作者机构：
  
  1. 中国科学院近代物理研究所
  2. 中国医学科学研究院肿瘤研究所
  4. ,北京,100021
- 作者简介：
- 基金信息：
  
  中国科学院“西部之光”人才培养计划 (XB980 6 0 4 )资助
- DOI：
  CLC： Q691.5
- Published：01 March 2002
- 稿件说明：
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[1]李文建,沈瑜,梁克.低剂量X射线照射诱导HeLa细胞存活的兴奋效应及适应性反应[J].核技术,2002(03):223-226.

LI Wenjian 1 LIANG Ke 2 SHEN Yu 2 1. Hormesis and adaptive response of survival in HeLa cells induced by low dose X-ray irradiation[J]. Nuclear techniques, 2002, (3): 223-226.
[1]李文建,沈瑜,梁克.低剂量X射线照射诱导HeLa细胞存活的兴奋效应及适应性反应[J].核技术,2002(03):223-226. DOI：

LI Wenjian 1 LIANG Ke 2 SHEN Yu 2 1. Hormesis and adaptive response of survival in HeLa cells induced by low dose X-ray irradiation[J]. Nuclear techniques, 2002, (3): 223-226. DOI：

摘要

采用集落形成法观察了低剂量X射线照射HeLa细胞的存活率。结果表明

小于 0 .5Gy的X射线照射细胞的存活率高于对照

得到了HeLa细胞存活的“兴奋效应”

而且在 0 .2 5Gy附近这种效应更为明显 ;低剂量D1（0 .0 5、0 .75Gy）的预照射降低了随后攻击剂量D2 对细胞的损伤程度

反映出低剂量照射可诱发细胞存活的“适应性反应”。

Abstract

The survival fraction in HeLa cells irradiated by low dose X-rays was observed using clone method. The results showed that the survival fraction in the cells irradiated by less than 0.5Gy X-rays was higher than control

”hormesis” of HeLa cell survival was obtained and was significant at doses near 0.25Gy; also

the damage degree of cells induced by the following irradiation was reduced because of pre-treating the cells with low dose D 1 of 0.05

0.75Gy; it was found from above that ”adaptive response” of cell survival was induced by the low dose irradiation.

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