Comparative element analysis on femur of antler hemo-treated ovariectomized Wistar rats by SRXRF

YANG Jianhong1; 2 FEI Yurong2 CAO Yi2; 3 WANG Ruilin2 HUANG Yuying4 HE Wei4 LIU Jing1 1

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Comparative element analysis on femur of antler hemo-treated ovariectomized Wistar rats by SRXRF

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- Comparative element analysis on femur of antler hemo-treated ovariectomized Wistar rats by SRXRF
- NUCLEAR TECHNIQUES Issue 5, (2007)
- 作者机构：
  
  1. 中国科学技术大学生命科学学院
  2. 中国科学院研究生院生物系
  3. 中国科学院高能物理研究所
  4. 中国科学技术大学生命科学学院合肥230026 中国科学院研究生院生物系北京,100049
  5. 北京100049 吉林大学生命科学学院长春,130000
- 作者简介：
- 基金信息：
  
  中国科学院研究生院院长基金资助(编号:Y1016)项目
- DOI：
  CLC： R285
- Published：01 May 2007
- 稿件说明：
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[1]杨建虹,费聿荣,曹毅,王瑞林,黄宇营,何伟,刘兢.鹿茸血处理前后去势大鼠股骨的SRXRF分析[J].核技术,2007(05):407-410.

YANG Jianhong1, 2 FEI Yurong2 CAO Yi2, 3 WANG Ruilin2 HUANG Yuying4 HE Wei4 LIU Jing1 1. Comparative element analysis on femur of antler hemo-treated ovariectomized Wistar rats by SRXRF[J]. Nuclear techniques, 2007, (5): 407-410.
[1]杨建虹,费聿荣,曹毅,王瑞林,黄宇营,何伟,刘兢.鹿茸血处理前后去势大鼠股骨的SRXRF分析[J].核技术,2007(05):407-410. DOI：

YANG Jianhong1, 2 FEI Yurong2 CAO Yi2, 3 WANG Ruilin2 HUANG Yuying4 HE Wei4 LIU Jing1 1. Comparative element analysis on femur of antler hemo-treated ovariectomized Wistar rats by SRXRF[J]. Nuclear techniques, 2007, (5): 407-410. DOI：

摘要

运用同步辐射X射线荧光（Synchrotron radiation X-ray fluorescence

SRXRF）技术分析鹿茸血处理前后的去势大鼠股骨元素含量及与骨密度（Bone mineral density

BMD）的关系。分别取出假手术组、去势组和去势后经鹿茸血处理组的雌性Wistar大鼠的左股骨

经SRXRF分析

结果显示:元素Ca、P、Zn和Sr之间有非常好的正相关性。与假手术组相比

去势大鼠股骨元素Ca、P、Zn和Sr的相对强度均有降低

其中元素Ca、P的相对强度明显降低（p<0.05）

其BMD也显著降低（p<0.05）

说明由于Ca和P元素的大量丢失

导致骨质疏松。用鹿茸血处理后

去势大鼠股骨元素Ca、P、Zn的相对强度都有不同程度的升高

因而其BMD也显著升高（p<0.05）

骨质疏松得到显著恢复。结果表明:鹿茸血有助于维持骨组织中微量元素Zn的含量

进而保持骨Ca和P的含量

从而提高BMD

减少骨质疏松的发生。

Abstract

To investigate the relationship between bone element contents and bone mineral density (BMD)

left fe- mur of sham-operated rats (SHAM

n=5)

ovariectomized rats (OVX

n=5) and antler hemo-treated ovariectomized rats (OVX+ antler hemo

n=5) were analyzed by synchrotron radiation X-ray fluorescence (SRXRF) microprobe. The results showed that there were very good positive correlations among contents of Ca

Zn and Sr. In comparison to the SHAM group

decreased relative intensities of Ca

Zn and Sr (especially Ca and P

p<0.05) were observed in femur of the OVX group

which showed significant decrease (p<0.05) of the BMD. The results indicate that loss of Ca and P in bone will cause osteoporosis. On the other hand

increased relative intensities of Ca

P and Zn in femur

and the BMD (p<0.05)

of the anlter hemo-treated OVX group were found

in comparison to the OVX group. This suggests that anlter hemo may help cure osteoporosis through maintaining bone contents of Zn

Ca and P

and increasing the BMD.

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