Due to its unique physical and chemical properties

DNA has recently become a promising material for building blocks in nanofabrication. Many researches focus on how to use DNA molecules as a template for nanowires. Molecular Combing technique is one of important methods to manipulate DNA molecules by using a water meniscus and form specific DNA nano-structures on surfaces. In this paper

by employing a modified molecular combing tech- nique

special patterns of DNA molecules was formed

and the interaction between liquid flows or meniscus and DNA molecules was analyzed

and the mechanism of manipulating DNA molecules by liquid was studied.