CHEN Libo YUAN Zhibin ZHU Ruisen. Applications of radiolabeled somatostatin analogs in the diagnosis and therapy of thyroid cancer[J]. Nuclear techniques, 2007, (7): 601-604.
CHEN Libo YUAN Zhibin ZHU Ruisen. Applications of radiolabeled somatostatin analogs in the diagnosis and therapy of thyroid cancer[J]. Nuclear techniques, 2007, (7): 601-604.DOI:
Applications of radiolabeled somatostatin analogs in the diagnosis and therapy of thyroid cancer
Patients with progressive metastatic(or recurrent) differentiated thyroid carcinoma that either do not take up radioioidine or are unresponsive to continued radioiodine therapy can be selected for somatostatin-receptor scinti-graphy(SRS) and high-dose peptide receptor radionuclide therapy(PRRT).PRRT with the β-particle-emitting ra-dionuclides yttrium-90(90Y) and lutetium-177(177Lu) gives the best results in terms of objective tumor response.Promising and novel radiolabeled somatostatin analogs used in the diagnosis and treatment of thyroid cancer are also discussed.