The labeling and synthesis study on tumor positive imaging   agent 5- （<sup>1</sup>8）F-Fluorouracil (<sup>18</sup>F-FU)

YUAN Zhibin

doi:null

您当前的位置：

首页 >

文章列表页 >

The labeling and synthesis study on tumor positive imaging agent 5- （¹8）F-Fluorouracil (¹⁸F-FU)

更新时间：2021-03-12

- The labeling and synthesis study on tumor positive imaging agent 5- （¹8）F-Fluorouracil (¹⁸F-FU)
- NUCLEAR TECHNIQUES Issue 5, (2001)
- 作者机构：
  
  1. 上海市第六人民医院,上海,200233
  2. 日本群马大学医学部,日本,371-8511
- 作者简介：
- 基金信息：
- DOI：
  CLC： R730.4
- Published：01 May 2001
- 稿件说明：
移动端阅览
[1]袁志斌,富吉腾美,井上登美夫,遠藤啓吾.亲肿瘤显像剂5-~(18)F-Fluorouracil(~(18)F-FU)的标记合成研究[J].核技术,2001(05):425-427.

YUAN Zhibin. The labeling and synthesis study on tumor positive imaging agent 5- （¹8）F-Fluorouracil (¹⁸F-FU)[J]. Nuclear techniques, 2001, (5): 425-427.
[1]袁志斌,富吉腾美,井上登美夫,遠藤啓吾.亲肿瘤显像剂5-~(18)F-Fluorouracil(~(18)F-FU)的标记合成研究[J].核技术,2001(05):425-427. DOI：

YUAN Zhibin. The labeling and synthesis study on tumor positive imaging agent 5- （¹8）F-Fluorouracil (¹⁸F-FU)[J]. Nuclear techniques, 2001, (5): 425-427. DOI：

摘要

用18 F F2 与Uracil的直接标记法合成了 5- 18F -Fluorouracil

探索18F -FU -PET显像对结肠直肠癌肝转移病人化疗前后疗效评价的意义。产品的放射化学纯 >95%

放射性得率为 60 %

pH值为 7

无菌性试验和热源试验均为阴性

这一结果为临床应用提供了保证。

Abstract

F-Fluorouracil were successfully labeled and synthesized using direct labeling method by 18 F/F 2 and Uracil. It was used for evaluating 18 F-FU-PET imaging for the colorectal carcinoma patients with liver metastases before and after chemotherapy. The radiochemical purity was above 95%

the radiochemical yield was about 60%

pH value was about 7 and both sterility and apyrogenicity test showed negative result. All these results guarantee its potential clinical usage.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

AI问答

Address：2019 Jialuo Road, Jiading, Shanghai, China Postal code：201800
Tel：021-39194977 Email：LHB@sinap.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 沪ICP备05005479号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
Total Visits：880886 Visits Today：413

⁰

The labeling and synthesis study on tumor positive imaging agent 5- （18）F-Fluorouracil (18F-FU)

DOI：

摘要

Abstract

关键词

Keywords

references

The labeling and synthesis study on tumor positive imaging agent 5- （¹8）F-Fluorouracil (¹⁸F-FU)