To develop a technique of one-day protocol of cerebral blood flow imaging with acetazolamide (ACZ) tablet stress and to discuss its clinic value

99m Tc-ECD SPECT data of regional cerebral blood flow (rCBF) study before and after taking ACZ (2g

oral) were collected in one day on 30 patients diagnosed as ischemic cerebralvascular disease. The responses of cerebralvascula before and after stress were observed and the positive rates of rest

stress test and CT examination were compared. The results show that the responses of rCBF to ACZ can be devided into four patterns. The positive rate of CT

rest test and combined test is 23.3%

26.7%

86.7% respectively. The positive rate of combined test is higher than that of rest test (p<0.05) and CT (p<0.01). It is concluded that the one-day protocol ACZ tablet test is time-saving and economic

because it can improve positive rate in cerebral ischemia and provide the information of cerebrovascular reserve capacity.