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1. 青岛大学医学院附属医院放免中心
2. 青岛大学医学院附属医院放免中心,青岛,266003
Published:01 May 2004
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[1]李雨升,王叙馥,于素清,余云云,杨立廷.~(99)Tc~m-MIBI心、肝时相显像对门脉性肝硬化门-体分流诊断的研究[J].核技术,2004(05):361-364.
LI Yusheng WANG Xufu YU Suqing YU Yunyun YANG Liting. A study on apiece time H/L ratio of 99Tcm-MIBI in diagnosis of cirrhosis with portal-systemic shunt[J]. Nuclear techniques, 2004, (5): 361-364.
通过心、肝时相显像对门脉性肝硬化门-体分流诊断的研究
验证门-体分流值的临床意义。方法是对10例正常者及36例门脉性肝硬化患者采用Tcm-MIBI直肠给药
分别在15—240min内的7个不同时相获取99H/L比值及SI
以便对肝硬化所致的门-体分流及程度进行分析。结果显示正常组与肝硬化A、B、C组H/L比值有极显著性差异(t分别为15.87、11.76、16.11
P<0.001)
SI与H/L比值有良好匹配性。肝硬化Child-pugh分级之间均有显著性差异(P<0.001)。C组6例患者所测的SI与手术中所测的门静脉自由压具有良好的相关性(r=0.926
P<0.001)。以上结果说明该方法可客观反映门脉性肝硬化门-体分流的程度
有助于肝硬化的分级及门脉压力的了解
可为临床提供有价值的诊断依据。
To evaluate the clinical value of portal-systemic shunt by the study on apiece time H/L ratio imaging in hepatocirrhosis
administration of Tcm-MIBI per rectum was performed in 10 healthy subjects and 36 patients with 99 cirrhosis by calculating H/L ratio and SI within 7 periods in 15—240 min to analyze the degree of hepatocirrhosis as- sociated with portal-systemic shunt. We have found that there is a marked difference between the H/L ratios of the control group and of the hepatocirrhosis group A
B
C ( t = 15.87
11.76
16.11
P < 0.001 )
and there is a good cor- relation between H / L ratio and SI ( r = 0.926
P < 0.001 ) . It is concluded that this is a safe method for evaluating portal-systemic shunt and thus helping obtain diagnostic index by estimating the degree of hepatocirrhosis and portal tension.
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