<sup>89</sup>Sr and<sup>153</sup>Sm-EDTMP for the treatment of painful disseminated skeletal metastasis

ZHANG Junning HONG Chengjiao ZHU Shoupeng

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⁸⁹Sr and¹⁵³Sm-EDTMP for the treatment of painful disseminated skeletal metastasis

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- ⁸⁹Sr and¹⁵³Sm-EDTMP for the treatment of painful disseminated skeletal metastasis
- NUCLEAR TECHNIQUES Issue 2, (2004)
- 作者机构：
  
  1. 苏州大学附属第一医院
  2. 苏州大学附属第一医院,215006
- 作者简介：
- 基金信息：
- DOI：
  CLC： R738.1
- Published：01 February 2004
- 稿件说明：
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[1]张军宁,洪承皎,朱寿彭.~(89)Sr、~(153)Sm内照射治疗骨转移癌引起骨痛的剂量研究[J].核技术,2004(02):138-142.

ZHANG Junning HONG Chengjiao ZHU Shoupeng. ⁸⁹Sr and¹⁵³Sm-EDTMP for the treatment of painful disseminated skeletal metastasis[J]. Nuclear techniques, 2004, (2): 138-142.
[1]张军宁,洪承皎,朱寿彭.~(89)Sr、~(153)Sm内照射治疗骨转移癌引起骨痛的剂量研究[J].核技术,2004(02):138-142. DOI：

ZHANG Junning HONG Chengjiao ZHU Shoupeng. ⁸⁹Sr and¹⁵³Sm-EDTMP for the treatment of painful disseminated skeletal metastasis[J]. Nuclear techniques, 2004, (2): 138-142. DOI：

摘要

对 Sr 或 Sm?EDTMP 治疗的 72 例（74 例次）骨转移癌病人的疗效、内照射靶器官的吸收剂量以及 89 153剂量响应关系进行了分析评价。结果表明，经 Sr 治疗的 31 例（33 例次）骨转移癌病人，治疗后骨痛反应属 89Ⅰ级者 15 例次，Ⅱ级者 14 例次，共 29 例次，占 87.88%；Ⅲ级者 4 例次，占 12.12%。未发现治疗后骨痛反应分级与 Sr 用量有明显关系；经 Sm?EDTMP 治疗的 41 例骨转移癌病人，治疗后骨痛反应属Ⅰ级者 19 89 153例，Ⅱ级者 18 例，共 37 例，占 90.24%；Ⅲ级者 4 例，占 9.76%。未发现治疗后骨痛反应分级与 Sm?EDTMP 153用量有明显关系。结果提示，亲骨性放射性药物 89Sr、153Sm?EDTMP 姑息治疗骨转移癌的骨痛效果显著。

Abstract

A retrospective analysis was performed on 72 patients with disseminated skeletal matestasis to evaluate the effect of strontium?89 or samarium?153 EDTMP therapy. There existed 87.88% of clinical response

12.12% of no response in the group treated with strontium?89 as compared with 90.24% of clinical response

9.76% no response in that treated with samarium?153 EDTMP; and there were no correlations between the treatment results and the amounts of isotopes administrated. The results suggest that strontium?89 or samarium?153 EDTMP therapy be the first choice in the palliative treatment for disseminated skeletal matestasis.

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89Sr and153Sm-EDTMP for the treatment of painful disseminated skeletal metastasis

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摘要

Abstract

关键词

Keywords

references

⁸⁹Sr and¹⁵³Sm-EDTMP for the treatment of painful disseminated skeletal metastasis