Clinical study of BGP, CT, PTH-M and β2-MG in serum and BMD for patients with CRF ante- and post-hemodialysis

SU Chenghai LI Qingru JIANG Yimin

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Clinical study of BGP, CT, PTH-M and β2-MG in serum and BMD for patients with CRF ante- and post-hemodialysis

更新时间：2021-03-12

- Clinical study of BGP, CT, PTH-M and β2-MG in serum and BMD for patients with CRF ante- and post-hemodialysis
- NUCLEAR TECHNIQUES Issue 1, (2004)
- 作者机构：
  
  1. 苏州大学附属第一医院核医学科
  2. 苏州大学附属第一医院核医学科,苏州,215006
- 作者简介：
- 基金信息：
- DOI：
  CLC： R459.5
- Published：01 January 2004
- 稿件说明：
移动端阅览
[1]苏成海,李清茹,江一民.血透患者血清骨钙素、降钙素、甲状旁腺素、骨密度及β_2-微球蛋白的临床研究[J].核技术,2004(01):66-69.

SU Chenghai LI Qingru JIANG Yimin. Clinical study of BGP, CT, PTH-M and β2-MG in serum and BMD for patients with CRF ante- and post-hemodialysis[J]. Nuclear techniques, 2004, (1): 66-69.
[1]苏成海,李清茹,江一民.血透患者血清骨钙素、降钙素、甲状旁腺素、骨密度及β_2-微球蛋白的临床研究[J].核技术,2004(01):66-69. DOI：

SU Chenghai LI Qingru JIANG Yimin. Clinical study of BGP, CT, PTH-M and β2-MG in serum and BMD for patients with CRF ante- and post-hemodialysis[J]. Nuclear techniques, 2004, (1): 66-69. DOI：

摘要

目的:探讨血透患者血清骨钙素（BGP）、降钙素（CT）、甲状旁腺素（PTH-M）、骨密度（BMD）及β2-微球蛋白（β2-MG）等的变化规律及其相互关系的临床价值。方法:用放射免疫（RIA）法测定40例慢性肾衰（CRF）血透患者透析前、后BGP、CT、PTH-M、及β2-MG等在血清中的变化

分析其间及其与部分生化指标之间的关系。其中测定了部分患者的BMD。结果:血透患者透析前BGP、CT、PTH-M及β2-MG均较对照组显著升高

透析后均较透析前显著降低;β2-MG与BGP、CT分别呈显著性正相关。19例血透患者BMD较对照组显著降低。结论:测定血清中BGP、CT、PTH-M及β2-MG等浓度及BMD

对于了解血透患者病情、疗效及估计预后等有一定临床价值。

Abstract

Objective: To explore the clinical value in the variation law and the relationships among BGP

PTH-M and β2-MG in serum of 40 patients with CRF ante- and post-haemodialysis and BMD of them. Methods: The relationships among BGP

PTH-M

β2-MG

AKP

BUN and Cr were analysed by testing their levels in serum of CRF patients with RIA; BMD of the lumbar spine in 19 of 40 patients with CRF was measured by dual-energy X-ray absorptiometry(DEXA). Results: The levels of BGP

PTH-M

β2-MG

AKP

BUN and Cr in serum of patients with CRF were higher than that of the controls. And that of patients with CRF in post-hemodialysis was very lower than that of those in ante-hemodialysis .The level of β2-MG in serum of patients with CRF was positively correlated with that of BGP and CT respectively. BMD of 19/40 patients with CRF were higher than that of the controls. Conclusion: There is a significant clinical value in testing β2-MG

BGP

PTH-M and CT concentrations in serum for analysing patient’s condition

assessing the treatment effect and estimating prognosis of patients with CRF.

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