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1. 南京铁道医学院科研所,南京,210009
2. 南京铁道医学院附属医院,南京,210009
3. 南京空军四五四医院,南京,210002
4. 南化医院,南京,210048
5. 南京市肿瘤医院,南京,210003
6. 南京铁道医
Published:01 May 2000
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[1]刘璐,腾皋军,姜藻,何士诚,谢松林,吴联生,宋副军,郭金和,方文,赵成桂,黄文旵.~(32)P-玻璃微球介入治疗肝细胞肝癌的临床初步应用[J].核技术,2000(05):316-322.
Preliminary clinical application of phosphorus-32 glass microspheres in interventional treating hepatocellular carcinoma[J]. Nuclear techniques, 2000, (5): 316-322.
采用 Seldingers穿刺法,导管超选择至肝固有动脉以远,灌注
32
P-玻璃微球(
32
P-GMS),对79例肝细胞肝癌(HCC)实施了99次内照射介入治疗。结果表明,A方案半年及1、2、3年生存率分别为100%、96.7%、56.7%和43.3%;B方案分别为97.9%、918%、61.2%和51.0%。经治后的中位生存时间为585天。多因素分析显示:肝功能、肿瘤大小、临床类型及
32
P-GMS在瘤体内积聚情况是影响生存率的预后因素。说明
32
P-GMS是一种安全、有效的肝癌治疗方法。
To evaluate the therapeutic effect of phosphorus-32 glass microsphere (
32
P-GMS) on hepatocellular carcinoma. By Seldinger’s procedure
super-selective catheterization was performed to the distal end of proper hepatic artery for instilling
32
p-GMS. Ninety-nine times of interventional internal irradiation were accomplished in 79 cases of hepatocellular carcinoma. Results shows that surviving rates in A or B regimen at half year
1
2 and 3 years were 100%
96.7%
56.7% and 43.3% or 97.9%
91.8%
61.2% and 51.0% respectively. The median surviving time after therapy was 585 days single multifactorial analysis revealed liver function
tumor size
clinical typing and accumulation of
32
P-GMS in the tumor mass and the therapeutic regime were the prognostic factors influencing the surviving rate of the patient. Conclusion:
32
P-GMS is a safe
effective and economic method for the therapeutic measure in treating hepatocellular carcinoma.
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