Trace elements in erythrocyte of patients with different thyroid functions

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Trace elements in erythrocyte of patients with different thyroid functions

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- Trace elements in erythrocyte of patients with different thyroid functions
- NUCLEAR TECHNIQUES Issue 2, (1999)
- 作者机构：
  
  1. 中国科学院高能物理研究所,北京,100080
  2. 中国医学科学院!中国协和医科大学北京协和医院北京,100730
- 作者简介：
- 基金信息：
  
  国家自然科学基金;中国科学院核分析技术开放实验室资助
- DOI：
  CLC： R581
- Published：01 February 1999
- 稿件说明：
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[1]刘年庆,刘平生,徐青,刘鹏,钱琴芳,朱立,赵志英,王正华,李彦芬,丰伟静.不同甲状腺激素水平病人红细胞中的微量元素[J].核技术,1999(02):119-122.

Trace elements in erythrocyte of patients with different thyroid functions[J]. Nuclear techniques, 1999, (2): 119-122.
[1]刘年庆,刘平生,徐青,刘鹏,钱琴芳,朱立,赵志英,王正华,李彦芬,丰伟静.不同甲状腺激素水平病人红细胞中的微量元素[J].核技术,1999(02):119-122. DOI：

Trace elements in erythrocyte of patients with different thyroid functions[J]. Nuclear techniques, 1999, (2): 119-122. DOI：

摘要

用质子激发Ｘ荧光和中子活化分析方法测量了不同甲状腺激素水平的甲状腺病人红细胞中的微量元素Ｋ、Ｃａ、Ｆｅ、Ｃｕ、Ｚｎ、Ｓｅ和Ｒｂ等的含量。用ＳＰＳＳ／ＰＣ软件中的单因素方差分析和相关性分析检验了不同组之间甲状腺激素和微量元素的差异和相关性。结果表明，不同甲状腺激素水平病人红细胞中Ｓｅ元素含量未见显著性差异。甲状腺功能低下组Ｚｎ的含量显著地高于甲亢和临界组，正常组则是介于甲低与甲亢和临界组之间。在甲亢组，元素间存在显著性的相关，甲状腺激素水平间（除ＴＳＨ外）也有显著性的相关，而元素和甲状腺激素间未见显著性相关。在甲低组，元素和激素间有较显著相关，特别是Ｚｎ的含量与Ｔ３和Ｔ４的比值及ＴＳＨ都有显著相关。

Abstract

The elements K

Se and Rb in erythrocyte of 78 cases with different thyroid hormone status have been measured by PIXE and INAA. According to status of thyroid hormones T3

TSH

FT3 and FT4 radioimmunoassayed

all patients were divided into four groups

i.e. hyperthyroid

normal

critical(one of thyroid hormones was abnormal) and hypothyroid.A comparison between four groups was performed and the correlations between different parameters (elements and thyroid hormones) were analyzed by oneway-anova and correlation using SPSS/PC statistical package respectively.The results show that the contents of Se between four groups are not significantly different (P< 0.05)

the content of Zn for hypothyroid group is significantly higher than these for hyperthyroid and critical groups

the content of Zn for normal is between that for hypothyroid and the other two groups. For hyperthyroid group

there are significant correlations between elements measured and between thyroid hormones (except TSH)

but not between elements and thyroid hormones. However for hypothyroid group

relatively strong correlations have been found between elements and thyroid hormones

specially Zn and T3/T4 ratio

and Zn and TSH.

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