Estimation of second primary cancers risk based on the treatment planning system

JIN Chufeng1; 3 LIU Hui2; 3 ZHENG Huaqing2; 3 CHENG Mengyun2; 3 LI Gui2; 3 SUN Guangyao1; 3 WU Yican1; 3 FDS Team 1

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Estimation of second primary cancers risk based on the treatment planning system

更新时间：2021-03-05

- Estimation of second primary cancers risk based on the treatment planning system
- NUCLEAR TECHNIQUES Vol. 34, Issue 10, (2011)
- 作者机构：
  
  1. 中国科学技术大学核科学技术学院
  2. 安徽省精确放疗工程技术研究中心
  3. 中国科学院等离子体物理研究所
- 作者简介：
- 基金信息：
  
  国家自然科学基金项目(No.30900386);安徽省自然科学基金项目(No.11040606Q55)资助
- DOI：
  CLC： R730.55
- Published：01 October 2011
- 稿件说明：
移动端阅览
[1]金雏凤,刘慧,郑华庆,程梦云,李贵,孙光耀,吴宜灿,FDS团队.基于放射治疗计划系统的二重癌风险预测分析[J].核技术,2011,34(10):772-776.

JIN Chufeng1, 3 LIU Hui2, 3 ZHENG Huaqing2, et al. Estimation of second primary cancers risk based on the treatment planning system[J]. Nuclear techniques, 2011, 34(10): 772-776.
[1]金雏凤,刘慧,郑华庆,程梦云,李贵,孙光耀,吴宜灿,FDS团队.基于放射治疗计划系统的二重癌风险预测分析[J].核技术,2011,34(10):772-776. DOI：

JIN Chufeng1, 3 LIU Hui2, 3 ZHENG Huaqing2, et al. Estimation of second primary cancers risk based on the treatment planning system[J]. Nuclear techniques, 2011, 34(10): 772-776. DOI：

摘要

放疗引发二重癌

已成为威胁癌症患者生存质量的重要因素。本文对临床放疗引发的二重癌进行风险预测分析

并对基于二重癌风险预测的计划评估方式展开了探索性研究。选择临床胰腺癌病例

使用FDS团队自主研发的精确放射治疗软件系统（Accurate/Advanced Radiotherapy System

ARTS）设计两个调强放疗计划

并对正常组织各重要器官的二重癌风险进行了预测

并以此对两种计划进行了评估。结果表明

该病人在接受放射治疗后

最有可能发生二重癌的是肾癌和胆囊癌（Plan 01:肾5.35%

胆囊3.10%;Plan 02:肾4.52%

胆囊4.57%）;二重癌分析结果表明:在满足临床剂量分布要求的前提下

Plan 02更为合理。本文建立了一种通过临床放疗计划系统预测二重癌风险的方法

并通过比较二重癌风险进行了临床放疗计划的评估分析。

Abstract

Estimates of second primary cancers risk after radiotherapy has become increasingly important for comparative treatment planning.A new method based on the treatment planning system to estimate the risk of second primary cancers was introduced in this paper.Using the Advanced/Accurate Radiotherapy Treatment System(ARTS)

a treatment planning system developed by the FDS team

the risk of second primary cancer was estimated over two treatment plans for a patient with pancreatic cancer.Based on the second primary cancer risk

the two plans were compared.It was found that

kidney and gall-bladder had higher risk to develop second primary cancer.A better plan was chosen by the analysis of second primary cancer risk.The results showed that this risk estimation method we developed could be used to evaluate treatment plans.

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