In this work

CdSe@ZnS quantum dots(QDs) distributed in the QDs-exposed adult drosophila and their stage-1 larva were characterized by synchrotron radiation micro X-ray fluorescence(μ-SRXRF) and laser scanning confocal microscope(LSCM)

respectively.The CdSe@ZnS QDs were exposed via the mouth to the adult drosophila.The μ-SRXRF elemental mapping of Cd

Se and Zn revealed that the elements were concentrated in the intestinal and reproductive system

indicating that QDs could accumulate in the intestinal and reproductive system.Obvious fluorescence signals were observed in the testis of stage-1 larva by LSCM technique.The results indicate the QDs via oral exposure could induce potential impact on placenta translocation and reproductive system.The results show that μ-SRXRF analysis is a novel method for the investigation of translocation of nanoparticle in the living organism.