Observation of correlation between chromosome aberrations and micronucleus in peripheral blood lymphocytes of macaqu induced by different way of γ-ray irradiation

Bingchai Zhu; Jiaben Lü; Tiehe Chen

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Observation of correlation between chromosome aberrations and micronucleus in peripheral blood lymphocytes of macaqu induced by different way of γ-ray irradiation

更新时间：2022-09-13

- Observation of correlation between chromosome aberrations and micronucleus in peripheral blood lymphocytes of macaqu induced by different way of γ-ray irradiation
- Nuclear Techniques Vol. 10, Issue 10, (1987)
- 作者机构：
  
  海军医学研究所
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Received：12 September 1986，
  
  Published：1987-10
- 稿件说明：
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Bingchai Zhu, Jiaben Lü, Tiehe Chen. Observation of correlation between chromosome aberrations and micronucleus in peripheral blood lymphocytes of macaqu induced by different way of γ-ray irradiation[J]. Nuclear techniques, 1987, 10(10): 53-54,64.
DOI：

Bingchai Zhu, Jiaben Lü, Tiehe Chen. Observation of correlation between chromosome aberrations and micronucleus in peripheral blood lymphocytes of macaqu induced by different way of γ-ray irradiation[J]. Nuclear techniques, 1987, 10(10): 53-54,64. DOI：

摘要

微核测定是七十年代初由Matter和Schmid建立的一种新的细胞遗传学测定体系，被人们誉为染色体损伤的快速测定方法

［1

2］

。尽管它的灵敏度低于染色体畸变分析，但该方法简单、可靠、迅速、易于掌握，因此，目前在辐射损伤、化学诱变及毒理学研究等方面已得到广泛应用。

Abstract

In this paper

the correlation between chromosome aberrations and micronucleus in peripheral blood T-lymphocytes of macaque induced by different ways of y-ray irradiation is reported. The results indicated that chromosome aberration frequencies and micronuclear frequecies were increased with the radiation dose under acute single

fractionated cumulative and chronic continuous exposure conditions. The T-lymphocyte micronuclear frequencies in peripheral blood were increased with the chromosome aberration frequencies

and correlation between them were rather close.

关键词

Keywords

references

B. E. Matter et al ., Mutat. Res ., 12 , 147 （ 1971 ）.

A. B. Krcpinsky et al ., Radiation-induced chromosomc damage in man , 1983 , p. 93 .

P. I. Coumtryman et al ., Mutat. Res ., 41 , 321 （ 1976 ）.

J. A. Heddle et al ., Mutat. Res ., 44 ， 63 （ 1977 ）.

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