After

3

H-muscone enter the body through different routes

it can pass through blood-brain-barrier rapidly and is distributed very rapidly in the viscera. We have observed metallic silver grains from

3

H-muscone in central nervous system with microscopy

it appeared diffusible distribution and it retained longer in the brain than in other tissues. But it deposits more in cerebella than in cerebral.

3

H-muscone also appeared diffusible distribution in other tissues and organs besides brain. In 30 minuted

3

H-muscone deposited in such order as follows: lungs

liver

skin

kidneys

heart

spleen

muscle. As stated above

it suggests that musk is also excreted through respiratory tract

skin and sweat glands in addition to biliary system and urinary system.