In-vivo distribution and thyroid imaging of 1-123-NaI

Yongchuan Wang; Qianmei Ji; Dequn Shen; Fasheng Fan; Yunxia Lan; Zhaoyi Zhao; Shouqing Wong; Weiyu He; Jiexi Lu; Xingen Yu; Lanping Yang; Jiong Zhang; Xichang Shi; Yongjian Li; Qixun Sun; Tiansen Huang; Changyu Xu; Hongzhu Jiang

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In-vivo distribution and thyroid imaging of 1-123-NaI

更新时间：2022-09-13

- In-vivo distribution and thyroid imaging of 1-123-NaI
- Nuclear Techniques Vol. 07, Issue 6, (1984)
- 作者机构：
  
  1.中国科学院上海原子核研究所
  2.上海市药品检验所
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Received：07 March 1983，
  
  Published：1984-06
- 稿件说明：
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Yongchuan Wang, Qianmei Ji, Dequn Shen, et al. In-vivo distribution and thyroid imaging of 1-123-NaI[J]. Nuclear techniques, 1984, 07(6): 60-60,58,70.
DOI：

Yongchuan Wang, Qianmei Ji, Dequn Shen, et al. In-vivo distribution and thyroid imaging of 1-123-NaI[J]. Nuclear techniques, 1984, 07(6): 60-60,58,70. DOI：

摘要

123

I核素的核性质较

131

I更适合于放射性药物设计要求和核医学临床应用，它具有十分优异的医用核性质

[1]

，有用

123

I替代

131

I进行甲状腺显像和功能测定的趋向

[2]

。其标记的有机化合物，如脂肪酸

[3]

、

-肾上腺能受体阻断剂、甾体激素等近年已受到放射性药物研究者的重视。我们采用天然锑靶干法成功地生产了Na

125

I注射液

[1]

，本文用此注射液观察在其小鼠体内分布，兔甲状腺扫描和

照相的结果。

Abstract

The I-123 obtained from

121

Sb (

2n)

123

I reaction and separated by dry distillation in this institute gave a thyroid uptake of 45 D %/g in distribution test. The ratio of thyroid uptake to that of other organs were 10—45 and has a maximum appeared in 1—6 after injection. Clear thyroid imagi ngs were obtained by both rectillinear scanner and gamma camera in 1—6 h after iv to rabbits.

关键词

Keywords

references

李永键等，核技术， 3 ， 31 （ 1983 ）。

V. Husak et al ., Isotopenpraxis , 16 , 361 ( 1980 ).

H. J. Machulla et al ., Eur. J. Nucl. Med ., 5 , 171 ( 1980 ).

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