Retention of <sup>152</sup>Eu and its radiation-induced chromosome aberrations on bone marrow cells

Shoupeng Zhu; Genfa Cao; Baofu Sun; Xiuying Zhao

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Retention of ¹⁵²Eu and its radiation-induced chromosome aberrations on bone marrow cells

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- Retention of ¹⁵²Eu and its radiation-induced chromosome aberrations on bone marrow cells
- Nuclear Techniques Vol. 13, Issue 6, (1990)
- 作者机构：
  
  苏州医学院
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Received：18 July 1988，
  
  Published：01 June 1990
- 稿件说明：
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Shoupeng Zhu, Genfa Cao, Baofu Sun, et al. Retention of ¹⁵²Eu and its radiation-induced chromosome aberrations on bone marrow cells[J]. Nuclear techniques, 1990, 13(6): 381-384.
DOI：

Shoupeng Zhu, Genfa Cao, Baofu Sun, et al. Retention of ¹⁵²Eu and its radiation-induced chromosome aberrations on bone marrow cells[J]. Nuclear techniques, 1990, 13(6): 381-384. DOI：

摘要

本文研究了

152

Eu在体内选择性蓄积部位所诱发的染色体畸变效应。发现无论摄入低或高放射性活度的

152

Eu后，均以在骨组织中的滞留量为最高，其后依次为肾、肝、肺和血液。呈高度选择性蓄积于骨组织中的

152

Eu，可诱发骨髓细胞染色体畸变，其畸变率随着摄入

152

Eu放射性活度的加大而相应增升。观察到在一个骨髓细胞中同时有两个以上畸变发生，

152

Eu可诱发的染色体结构异常为染色单体型畸变，其中主要为染色单体断裂。

Abstract

This paper describes the correlation between the retention of

152

Eu and its radiation induced chromosome aberrations on bone marrow cells. The results indicated that

152

Eu was largely localized in bone

and then in kidney

liver

lung and blood. When fission product

152

Eu was selectively accumulated in bone

it caused chromosome aberrations on bone marrow cells. The chromosome aberrations were increased with uptake of

152

Eu radioactivity. Among the types of chromosome aberrations induced by

152

chromatid breakage was predominant. Two chromatid breakages in one cell were observed.

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references

R. O. McClellen , Aerosp. Med . , 36 （ 1965 ）, 10 .

朱寿彭等，中国药理学报， 3 （ 1982 ）， 3 : 197 。

朱寿彭等，中华劳动卫生职业病杂志， 2 （ 1984 ）, 341 。

朱寿彭等，中国药理学报， 7 （ 1986 ）, 4 : 381 。

朱寿彭，放射毒理学，第一版，原子能出版社。北京， 1983 年，第246页。

M. Hollstein , Mutat. Res . , 65 （ 1979 ）, 133 .

S. Nakai , Radiation-induced chromosome damage in man , Liss-New York , 1983 , p. 71 .

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Retention of 152Eu and its radiation-induced chromosome aberrations on bone marrow cells

DOI：

摘要

Abstract

关键词

Keywords

references

Retention of ¹⁵²Eu and its radiation-induced chromosome aberrations on bone marrow cells