Prussian blue (PB) can enhance elimination of

134

Cs in rat and

137

Cs in human subjects

not only in early period but also in late period. When each rat was given orally 50 mg/kg of PB

the total elimination rate of

134

Cs in 72 hours was 53.9%

When the rat received orally 500 mg/kg of PB each day which lasted for 6 days

the total elimination rate of

134

Cs in 7 days was 94.3%.

The toxicity of PB was quite low. The doses as high as 40—800 times of 50mg/kg PB did not cause any acute and early toxic effects on mice

rats and dogs.