The effect of radio-nuclide <sup>211</sup>At on the frequency of lymphocytes Ag-NORs culture in vitro

Yali Zhao; Yizhong Wang; Zishu Wang; Wenyuan Chen; Maolun Zhou; Daoquan Xu; Shuyuan Zhang

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The effect of radio-nuclide ²¹¹At on the frequency of lymphocytes Ag-NORs culture in vitro

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- The effect of radio-nuclide ²¹¹At on the frequency of lymphocytes Ag-NORs culture in vitro
- Nuclear Techniques Vol. 12, Issue 7, (1989)
- 作者机构：
  
  1.四川大学
  2.四川大学原子核科学技术研究所
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Received：12 September 1988，
  
  Published：1989-07
- 稿件说明：
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Yali Zhao, Yizhong Wang, Zishu Wang, et al. The effect of radio-nuclide ²¹¹At on the frequency of lymphocytes Ag-NORs culture in vitro[J]. Nuclear techniques, 1989, 12(7): 440-443.
DOI：

Yali Zhao, Yizhong Wang, Zishu Wang, et al. The effect of radio-nuclide ²¹¹At on the frequency of lymphocytes Ag-NORs culture in vitro[J]. Nuclear techniques, 1989, 12(7): 440-443. DOI：

摘要

本文报道了

211

At-Te胶体对体外培养的人淋巴细胞Ag-NORs频率的影响。实验结果表明：

-辐射对经PHA刺激后已相继进入细胞增殖周期的淋巴细胞的Ag-NORs频率基本无影响；而对刚接受PHA刺激正在转化的淋巴细胞，低剂量辐照时，Ag-NORs频率明显升高，似乎具有刺激rRNA基因表达活性和增强转录作用；高剂量辐照时，Ag-NORs频率下降，具有一定抑制作用。

Abstract

The effect of

211

At-tellurium colloid on the frequency of lymphocytes Ag-NORs culture in vitro was studied. The result showed that the alpha-radiation had no effect upon the frequency of Ag-NORs of lymphocytes which had been stimulated by PHA and entered in succession proliferation cycle of cell; but for the lymphocytes in transforming immediately being stimulated by PHA

in low irradiation does

the frequency of Ag-NORs was obviously increased

it seemed to be capable of stimulating the activation of rRNA gene and increasing transcription

while in high irradiation dose

it had some restraining effect.

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Keywords

references

I. Brown et al . , Int. J . Appl. Radiat. , （ 1982 ）, 33 : 75 .

W. J. Bateman et al . , Int. J. Nucl. Med. Biol. , （ 1983 ）, 10 : 241 .

W. M. Howell , Chromosoma （ Berl ） , 62 （ 1977 ）, 361 .

邵岳生等，四川大学学报（自然科学版）， 25 （ 1988 ）, 105 。

R. Baserga 等译，细胞繁殖的生物学，北京师范大学出版社， 1985 年，第155页。

T. D. Luckey , Health Physics , 43 （ 1982 ）, 771 .

P. E. Bryant , Int. J. Radiat. Biol. , ( 1976 ), 327 .

朱壬葆等，辐射生物学，科学出版社， 1987 年，第128页。

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The effect of radio-nuclide 211At on the frequency of lymphocytes Ag-NORs culture in vitro

DOI：

摘要

Abstract

关键词

Keywords

references

The effect of radio-nuclide ²¹¹At on the frequency of lymphocytes Ag-NORs culture in vitro