Positron annihilation in interferon affected cells

Baifen Shi; Shuqin Zhou; Jingpei Li; Jingsheng Zhu

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Positron annihilation in interferon affected cells

更新时间：2022-08-16

- Positron annihilation in interferon affected cells
- Nuclear Techniques Vol. 12, Issue 7, (1989)
- 作者机构：
  
  1.安微医科大学
  2.中国科技大学
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Received：04 December 1987，
  
  Published：1989-07
- 稿件说明：
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Baifen Shi, Shuqin Zhou, Jingpei Li, et al. Positron annihilation in interferon affected cells[J]. Nuclear techniques, 1989, 12(7): 427-429.
DOI：

Baifen Shi, Shuqin Zhou, Jingpei Li, et al. Positron annihilation in interferon affected cells[J]. Nuclear techniques, 1989, 12(7): 427-429. DOI：

摘要

测量了用干扰素（3.6×10

Iu/mgPr）处理的Hep-2细胞和对照细胞的正电子湮没寿命谱。正电子寿命谱分成三个寿命成分。观察到干扰素作用细胞和对照细胞间O-Ps拾取湮没长寿命成分的明显差别。干扰素作用细胞的τ

比对照细胞长，而

则前者比后者低。而τ

的乘积是增大的。结果表明干扰素作用细胞的生物大分子结构体积增加。细胞的抗病毒状态与上述变化的关系需进一步研究。

Abstract

Positron annihilation lifetime spectra were measured for the Hep-2 cell cultures treated with the interferon (3.6×10

Iu/mg Pr.) and control cells. The positron lifetime spectra were resolved into three lifetime components. The clear difference of the long-lifetime components related to the pick-off annihilation of ortho positronium between the interferon affected cells and the control cells was observed. The result showed that τ

in the interferon treated cells was longer than that in control cells

and I

in the former was lower than that in the latter

but the product of τ

was augmented. As to free volume model

the result suggested that biological macromolecular conformation volume of the interferon affected cells was increased. The relation between such change and the anti-virus condition of the cell calls for more fuather studies.

关键词

Keywords

references

张咏南编，干扰素入门，安徽科学技术出版社， 1984 年。

P. G. Coleman et al . eds. , Positron annihilation , North-Holland Publishing Company , 1982 , p. 928 .

ibid , 1982 , p. 930

S. Y. Chuang et al . , ibid , 1982 , p. 919 .

R. K. Willson et al . , Phys. Rev. , 129 （ 1963 ）, 2091 .

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