Comparative studies on the effect of PHA-activated lymphocytes micronuclei in monkeys during and after <italic style="font-style: italic">γ</italic>-irradiation under different conditions

Lü Jiaben; Binchai Zhu; Zongwu Wang; Lanjin Wang; Tiehe Chen

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Comparative studies on the effect of PHA-activated lymphocytes micronuclei in monkeys during and after γ-irradiation under different conditions

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- Comparative studies on the effect of PHA-activated lymphocytes micronuclei in monkeys during and after γ-irradiation under different conditions
- Nuclear Techniques Vol. 12, Issue 1, (1989)
- 作者机构：
  
  海军医学研究所
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Received：18 February 1987，
  
  Published：1989-01
- 稿件说明：
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Lü Jiaben, Binchai Zhu, Zongwu Wang, et al. Comparative studies on the effect of PHA-activated lymphocytes micronuclei in monkeys during and after γ-irradiation under different conditions[J]. Nuclear techniques, 1989, 12(1): 50-53.
DOI：

Lü Jiaben, Binchai Zhu, Zongwu Wang, et al. Comparative studies on the effect of PHA-activated lymphocytes micronuclei in monkeys during and after γ-irradiation under different conditions[J]. Nuclear techniques, 1989, 12(1): 50-53. DOI：

摘要

本文研究了急性一次、分次累积和慢性连续

线照射对猕猴外周血PHA-激活淋巴细胞微核的效应。发现多分次及慢性照射所诱发的微核效应变化规律极为相似，较急性组轻微得多。不同方式

线照射期间，各组PHA-激活淋巴细胞微核率均随照射剂量增加而显著增高，并于停照后6个月恢复到照前水平。该结果表明，PHA-激活淋巴细胞核不仅对急性，而且对慢性辐射损伤的评价，都是一项极有价值的生物学指标。

Abstract

The effect of

-radiation dose

under acute single

fractionated cumulative and chronic continuous irradiation conditions

on PHA-activated lymphocytes micronuclear frequency in peripheral blood of monkeys is reported.

The results indicate that the micronuclear frequency

which is increased significantly with increasing doses under all conditions

will be recovered to normal in the 6th month after the termination of irradiation. It is also found that the laws of the micronuclear effect are very similar under the multifractionated and the chronic irradiation conditions

but they are much less than the acute result.

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references

杨家宽等，核防护，（ 1980 ）, 3 : 64 。

E. Unger , Strahlentherapie , 156 （ 1980 ） 1 : 46 .

T. Ishihara et al . , The radiation-induced chromosome damage in man , New York 1983 , p. 561 .

全国医用诊断X线工作者剂量与效应关系研究协作组淋巴细胞微核专题组，中华放射医学与防护杂志， 4 （ 1984 ）， 5 : 49 。

T. Ishihara et al . , The radiation-induced chromosome damage in man , New York , 1983 , p. 93 .

吕家本等，中华放射医学与防护杂志， 7 （ 1987 ）, 3 : 201 。

R. Rugh , Am. J. Roentgenology , 91 （ 1964 ）, 192 .

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Related Institution

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Comparative studies on the effect of PHA-activated lymphocytes micronuclei in monkeys during and after γ-irradiation under different conditions

DOI：

摘要

Abstract

关键词

Keywords

references