A study on efficiency of excitation labelling with tritium

Shaofeng Ding; Yanhui Shi; Zhaoxing Meng; Boli Liu; Mingguang Yi; Decun Shen

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A study on efficiency of excitation labelling with tritium

更新时间：2022-08-16

- A study on efficiency of excitation labelling with tritium
- Nuclear Techniques Vol. 11, Issue 1, (1988)
- 作者机构：
  
  1.北京师范大学
  2.中国原子能科学研究院
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：1988-01
- 稿件说明：
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Shaofeng Ding, Yanhui Shi, Zhaoxing Meng, et al. A study on efficiency of excitation labelling with tritium[J]. Nuclear techniques, 1988, 11(1): 41-42.
DOI：

Shaofeng Ding, Yanhui Shi, Zhaoxing Meng, et al. A study on efficiency of excitation labelling with tritium[J]. Nuclear techniques, 1988, 11(1): 41-42. DOI：

摘要

川芎嗪是从川芎中分离得到的生物碱，对于治疗急性闭塞性脑血栓有良好疗效，受到广泛重视。我们以川芎嗪为底物，硅－铝小球作支持体，用电炉丝把浸沾一定量川芎嗪的硅－铝小球束缚成柱体，分别放入高频放电曝射瓶内和微波氚化系统的冷指上，进行高频放电和微波放电激发氚气标记川芎嗪，制备了不同比放射性的

H-川芎嗪。高频放电制备的

H-川芎嗪比度为0.25—8.89GBq/mmol。微波放电制备的

H-川芎嗪比度为0.29—6.75GBq/mmol。我们发现氚化物的比度和底物所在的位置成正态分布关系。用正态分布曲线公式拟合了各个实验点出现的几率并作图，两者基本相似。

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