Dynamics study on ligand exchange reaction between <sup>99m</sup>Tc-glucoheptonate and carbomethoxy-isopropylisonitrile

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Dynamics study on ligand exchange reaction between ^99mTc-glucoheptonate and carbomethoxy-isopropylisonitrile

更新时间：2022-08-16

- Dynamics study on ligand exchange reaction between ^99mTc-glucoheptonate and carbomethoxy-isopropylisonitrile
- Nuclear Techniques Vol. 11, Issue 1, (1988)
- 作者机构：
  
  北京师范大学
- 作者简介：
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- DOI：
  CLC：
- Published：1988-01
- 稿件说明：
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Yi Wei, Xuebin Wang, Boli Liu, et al. Dynamics study on ligand exchange reaction between ^99mTc-glucoheptonate and carbomethoxy-isopropylisonitrile[J]. Nuclear techniques, 1988, 11(1): 8.
DOI：

Yi Wei, Xuebin Wang, Boli Liu, et al. Dynamics study on ligand exchange reaction between ^99mTc-glucoheptonate and carbomethoxy-isopropylisonitrile[J]. Nuclear techniques, 1988, 11(1): 8. DOI：

甲酯异丙基异腈（CPI）是特丁基异腈（TBI）的衍生物。它是新近发展起来的第二代Tc标记的异腈类心肌显像剂中较好的一种。

本文首次用纸层析法研究了介质pH、CPI浓度、葡庚糖酸钙（Ca-GH）含量、

99m

Tc-GH浓度及温度对下列配体交换反应的反应速率

及最终交换率

∞

（相当于

99m

Tc-CPI的标记率）的影响：

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Dynamics study on ligand exchange reaction between 99mTc-glucoheptonate and carbomethoxy-isopropylisonitrile