The sythesis, labelling and animal distribution of a tumor imaging agent <sup>99m</sup>Tc-EDDA

Yiguo Zhou; Yun Zhao; Tong Zhu

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The sythesis, labelling and animal distribution of a tumor imaging agent ^99mTc-EDDA

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- The sythesis, labelling and animal distribution of a tumor imaging agent ^99mTc-EDDA
- Nuclear Techniques Vol. 11, Issue 1, (1988)
- 作者机构：
  
  上海医科大学药学院
- 作者简介：
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- DOI：
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- Published：1988-01
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Yiguo Zhou, Yun Zhao, Tong Zhu. The sythesis, labelling and animal distribution of a tumor imaging agent ^99mTc-EDDA[J]. Nuclear techniques, 1988, 11(1): 4-5.
DOI：

Yiguo Zhou, Yun Zhao, Tong Zhu. The sythesis, labelling and animal distribution of a tumor imaging agent ^99mTc-EDDA[J]. Nuclear techniques, 1988, 11(1): 4-5. DOI：

摘要

锝-99m-乙二胺-N

N-二乙酸（

99m

Tc-EDDA）具有亲肿瘤性质。动物实验证明

99m

Tc-EDDA是一个优良的恶性肿瘤显像剂。

本文从乙二胺和乙酸乙酯为起始原料合成N-乙酰乙二胺（A-EDA），A-EDA与溴乙酸反应得到N-乙酰－乙二胺-N'，N'-二乙酸（A-EDDA），A-EDDA经过氢氧化钠和计算量盐酸处理，得到最终产品u-EDDA。

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The sythesis, labelling and animal distribution of a tumor imaging agent 99mTc-EDDA

DOI：

摘要

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The sythesis, labelling and animal distribution of a tumor imaging agent ^99mTc-EDDA