Studies and preparation of <sup>99m</sup>Tc-hexakis (t-butylisonitrile) kit -a myocardial perfusion imaging agent and its preliminary clinical applications

Huiyang Zhao; Quansheng Li; Liren Shao; Yuzhi Guo; Qinfang Kuang; Bin Lou; Ping Fang

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Studies and preparation of ^99mTc-hexakis (t-butylisonitrile) kit -a myocardial perfusion imaging agent and its preliminary clinical applications

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- Studies and preparation of ^99mTc-hexakis (t-butylisonitrile) kit -a myocardial perfusion imaging agent and its preliminary clinical applications
- Nuclear Techniques Vol. 10, Issue 6, (1987)
- 作者机构：
  
  1.上海医科大学附属中山医院
  2.上海医科大学药学院
  3.江苏省原子医学研究所
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Received：08 April 1986，
  
  Published：1987-06
- 稿件说明：
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Huiyang Zhao, Quansheng Li, Liren Shao, et al. Studies and preparation of ^99mTc-hexakis (t-butylisonitrile) kit -a myocardial perfusion imaging agent and its preliminary clinical applications[J]. Nuclear techniques, 1987, 10(6): 50-52,63,64.
DOI：

Huiyang Zhao, Quansheng Li, Liren Shao, et al. Studies and preparation of ^99mTc-hexakis (t-butylisonitrile) kit -a myocardial perfusion imaging agent and its preliminary clinical applications[J]. Nuclear techniques, 1987, 10(6): 50-52,63,64. DOI：

摘要

99m

锝－特丁基异腈（

99m

Tc-TBI）是第一个较成功地进入临床试用阶段的

99m

锝标记心肌显像剂

[1]

。

99m

Tc-TBI可用还原法

[2]

或配体交换法

[3]

标记。本文采用自制的TBI与改进的配体交换法药盒，检测15例，进行静息与运动试验时的平面与断层显像，并与

201

T1心肌显像对照，以探讨

99m

Tc-TBI临床应用的特点。

Abstract

This paper reports the study and preparation of

99m

Tc-hexakis (t-butylisonitrile) kit. The radiochemical purity was over 95%.

15 cases were studied with kits

included normal control 3 cases

coronary artery disease 5 cases

aneurysm 2 cases

arrhythmia 3 cases

virus myocarditis 1 case

exudative percarditis 1 case.

these indicated that

99m

Tc-TBI myocardial perfusion agent would be used effectively in detecting heart diseases.

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Keywords

references

A. G. Jones et al. , J. Nucl, Med. , 23 , 5 , 16 ( 1982 ).

A. G. Jones et al. , Int. J. Nucl. Med. Biol. , 11 , 3/4 , 225 ( 1984 ).

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国毓智等，核技术， 11 , 51 ( 1986 )。

E. Deutech et al. , J. Nucl. Med. , 22 , 897 ( 1981 ).

李铨生等，中华核医学杂志， 5 ， 2 , 103 ( 1985 )。

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ibid , 25 , 5 , 15 ( 1984 ).

王学斌等，核技术 , 4 , 35 ( 1986 )。

刘秀杰等，中华核医学杂志 , 6 , 4 , 249 ( 1986 )。

唐谨等，中华核医学杂志 , 6 , 1 , 6 ( 1986 )。

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Related Institution

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Studies and preparation of 99mTc-hexakis (t-butylisonitrile) kit -a myocardial perfusion imaging agent and its preliminary clinical applications

DOI：

摘要

Abstract

关键词

Keywords

references

Studies and preparation of ^99mTc-hexakis (t-butylisonitrile) kit -a myocardial perfusion imaging agent and its preliminary clinical applications