The rapid synthesis and biological tests of <sup>123</sup>I-hippuran

Fasheng Fan; Zentang Zhou; Dequn Shen; Yun Wang; Yifang Ye; Qixun Sun; Yongchuan Wang; Qianmei Ji; Jiong Zhang; Yongjian Li

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The rapid synthesis and biological tests of ¹²³I-hippuran

更新时间：2022-08-16

- The rapid synthesis and biological tests of ¹²³I-hippuran
- Nuclear Techniques Vol. 05, Issue 3, (1982)
- 作者机构：
  
  中国科学院上海原子核研究所
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：1982-06
- 稿件说明：
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Fasheng Fan, Zentang Zhou, Dequn Shen, et al. The rapid synthesis and biological tests of ¹²³I-hippuran[J]. Nuclear techniques, 1982, 05(3): 68-69,72.
DOI：

Fasheng Fan, Zentang Zhou, Dequn Shen, et al. The rapid synthesis and biological tests of ¹²³I-hippuran[J]. Nuclear techniques, 1982, 05(3): 68-69,72. DOI：

摘要

123

I－邻碘马尿酸（下称

123

I-OIH）由于

123

I半衰期短、γ射线能量合适、无β射线发射，较之常用的

131

I-OIH，不仅可使病人接受剂量显著减小，而且成像清晰、可提高诊断的准确性，是目前较理想的肾动态显像剂。

Abstract

123

I-hippuran was synthesized from home-made Na

123

I and othoiodohippuric acid(OIH) by fusion at 180℃ within 3 minutes. It gave yields of

90% with

98% of radiochemical purity. The mice distributions and renal γ-camera imagings of rabbit and dog with

123

I-OIH thus obtained shew it to be promise in clinical application.

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references

H. Ellas et al . , Int. J. Appl. Radiat. Isotopes , 24 , 463 ( 1973 ).

G. Westera et al . , ibid , 29 , 339 ( 1978 ).

M. L. Thakur et al . , ibid , 26 , 319 ( 1975 ).

J. A. Bijl et al . , J. Radioanalytical Chemistry , 35 , 55 ( 1977 ).

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The rapid synthesis and biological tests of 123I-hippuran

DOI：

摘要

Abstract

关键词

Keywords

references

The rapid synthesis and biological tests of ¹²³I-hippuran