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生命科学发展到一定阶段,人们就开始认识到,用标记原子或分子进行示踪工作对阐明各种生命现象有十分重要的意义。因此,1927到1932年短短五年内
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H等被发现不久,稳定同位素示踪技术很快就开展起来,应用于生物、医学科学,作出了不少重要贡献。四十年代中期,人造放射性同位素问世,和当时的稳定同位素相比,它成本较低、探测方便且灵敏度较高,可进行放射自显影工作,有的还可在体外探测其在整体内的分布情况,于是稳定同位素的应用进入低潮。只是当某些元素(如氮)没有合用的放射性同位素时,或某些工作只能用稳定同位素技术才能解决时,人们才考虑使用稳定同位素。
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