回旋加速器制备放射性枸橼酸镓 (<sup>67</sup>Ga) 注射液

声洋 陈; 留芳 张; 景芝 刘; 蓉珍 曹

您当前的位置：

首页 >

文章列表页 >

回旋加速器制备放射性枸橼酸镓 (⁶⁷Ga) 注射液

更新时间：2022-08-16

- 回旋加速器制备放射性枸橼酸镓 (⁶⁷Ga) 注射液
- 核技术 Vol. 03, Issue 3, (1980)
- 作者机构：
  
  Shanghai Institute of Nuclear Research, Chinese Academy of Sciences
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Received：29 November 1979，
  
  Published：1980-06
- 稿件说明：
移动端阅览
声洋陈, 留芳张, 景芝刘, et al. 回旋加速器制备放射性枸橼酸镓 (⁶⁷Ga) 注射液[J]. 核技术, 1980, 03(3): 15-20.
DOI：

声洋陈, 留芳张, 景芝刘, et al. 回旋加速器制备放射性枸橼酸镓 (⁶⁷Ga) 注射液[J]. 核技术, 1980, 03(3): 15-20. DOI：

摘要

Abstract

本文叙述了在1.2米回旋加速器的外靶上，用26.8MeV的α粒子束和13.4MeV的

粒子束，分别轰击天然铜靶和天然锌靶，制备无载体

Ga的方法。其厚靶产额分别为165µCi/µAh和350 µCi/µAh。无载体

Ga的化学分离采用异丙醚溶剂萃取法。枸橼酸镓（

Ga）注射液的制备采用3~3.8%枸橼酸钠溶液浸取。整个工艺流程需时4小时，操作简便，安全可靠，其化学产率可达90%以上。

The production of carrier-free gallium-67 at external target of the 1.2M cyclotron is described. It was produced by bombardment of natural copper with 26.8 MeV

and natural zinc with 13.4 MeV deuterium

gave thick-target yields of 165μCi/μAh and 350µCi/μAh

respectively. Radiochemical separation of carrier-free gallium-67 from target was carried out by isopropyl ether extraction. Gallium-67 citrate injection was prepared by sodium citrate leaching. The overall chemical procedure took 4 hours and the operations were simple and safe. The chemical yield was greater than 90%.

关键词

Keywords

references

中科院上海原子核所能谱组，原子核物理（1978年会议选编），原子能出版社， 1978 , P. 118 .

C. L. Edwards & amp; R. L. Hayes , ORAU-107 , 110 ( 1968 ).

R. L. Hayes ., Nucl. Med. , 8 , 3 , 183 ( 1978 ).

S. M. Larson , ibid , 8 , 3 , 193 ( 1978 ).

L. C. Brown et al .， Int. J. Appl. Radiat. Isotope . , 24 , 11 , 651 （ 1973 ).

J. Gruverman Irwin et al ., ibid , 5 , 1 , 21 ( 1959 ).

F. Helur et al ., Radiopharmaceuticals & labelled compounds , IAEA , 1973 ,P. 317 .

D. J. Silvester et al ., Int, J. Appl. Radiat. Isotope. , 21 , 10 , 630 ( 1970 ).

H. B. Hupf et al ., ibid , 22 , 2 , 75 ( 1970 ).

L. C. Brown , ibid , 12 , 11 , 710 ( 1971 ).

J. Steyn et al ., ibid , 24 , 7 , 369 ( 1973 ).

M. Vlatkolc et al ., ibid , 26 , 6/7 , 377 ( 1975 ).

J. R. Dahl et al ., ibid , 23 , 9 , 431 ( 1972 ).

E. W. Martin et al .， Remington's practice of pharmary , 12 ed. Mark Pulisking Comp. , 1961 , P. 198 .

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

AI问答

Address：2019 Jialuo Road, Jiading, Shanghai, China Postal code：201800
Tel：021-39194977 Email：LHB@sinap.ac.cn
Technical support is provided by Beijing Founder electronics co., LTD 沪ICP备05005479号-1 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
Total Visits：880099 Visits Today：621

⁰

回旋加速器制备放射性枸橼酸镓 (67Ga) 注射液

DOI：

摘要

Abstract

关键词

Keywords

references

回旋加速器制备放射性枸橼酸镓 (⁶⁷Ga) 注射液